The First Affiliated Hospital Of Zhengzhou University

This phase 3 trial tests whether a new combination of drugs (anlotinib plus benmelstobart) works better than the current standard treatment for advanced esophageal cancer that has certain gene mutations. About 578 adults with this cancer who have not had prior treatment will be r…

This study tests a combination of two drugs, sacituzumab tirumotecan and bevacizumab, in 30 women with platinum-resistant recurrent ovarian cancer. The goal is to see if the combo can shrink tumors and delay cancer growth better than current options. Participants must have had 1 …

This study tests if the clot-busting drug tenecteplase can help people who have a stroke and are treated 4.5 to 9 hours after symptoms begin. About 564 participants will receive either tenecteplase or a placebo, along with aspirin. The goal is to see if the drug improves recovery…

This study tests a new drug combination for people with advanced stomach cancer that has worsened after initial treatment. The experimental drug IBI363 aims to help the immune system attack cancer cells, and is given with bevacizumab, with or without nab-paclitaxel. About 50 adul…

This study tests whether adding blood flow restriction training (using a cuff to lightly limit blood flow during exercise) and brain stimulation (rTMS) to standard rehab can help stroke patients with paralysis on one side move better. 69 adults who had a stroke will be split into…

This study tests a special rinse (menthol plus simethicone) during colonoscopy to reduce muscle spasms and clear foam, making it easier for doctors to see polyps. About 500 adults getting a colonoscopy will be randomly assigned to receive the rinse or standard care. The goal is t…

This study is testing if spraying a menthol solution during a colonoscopy can relax intestinal muscles and reduce painful spasms. Researchers will enroll 440 adults to see if this approach makes the procedure more comfortable and helps doctors spot more precancerous growths. The …