New hope for tough esophageal cancer: drug combo targets gene mutations
NCT ID NCT07446335
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a new combination of drugs (anlotinib hydrochloride plus benmelstobart) works better than the current standard treatment (toripalimab plus chemotherapy) for people with advanced esophageal cancer that has certain gene mutations. The trial will include 578 adults who have not had prior treatment for advanced disease. The main goals are to see if the new combo helps people live longer without their cancer growing and to check for side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
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Other studies related to the condition(s) this trial covers.
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