Sunnybrook Health Sciences Centre

This study tested a combination of three drugs (DPX-Survivac, low-dose cyclophosphamide, and pembrolizumab) in 25 adults with diffuse large B-cell lymphoma that had come back or not responded to previous treatments. The goal was to see if the immune system could be boosted to shr…

This study tested whether washing a surgical incision with an antiseptic or salt water before closing it can prevent infections after surgery. Over 2,500 adults having abdominal or groin surgery were randomly assigned to receive one of two types of wound washing or no washing at …

This study looked at whether giving antibiotics after draining a perianal abscess (a painful infection near the anus) can stop a fistula (an abnormal tunnel) from forming. It included 15 adults who had surgery for the abscess. The main goal was to see if a larger study is possibl…

This study tested whether a new, high-resolution ultrasound (micro-ultrasound) can find aggressive prostate cancers as well as MRI does when guiding biopsies. Over 800 men with suspected prostate cancer took part. The goal was to see if micro-ultrasound could be a simpler, cheape…

This study tested whether Dex4 chewable tablets work as well as the standard sugary drink for diagnosing gestational diabetes in pregnant women. 31 women who had a positive initial screening took both tests to compare blood sugar levels and side effects. The goal was to see if th…

This study looked at whether drinking coffee after abdominal surgery can help the bowels start working again sooner. About 174 adults who had surgery were given either regular coffee, decaf coffee, or warm water three times a day. The main goal was to see if a larger study is pos…

This study looked at whether applying ice packs to surgical cuts every 4 hours for 3 days helps adults recover better after chest, belly, or groin surgery. 196 patients took part, with some getting ice plus standard care and others standard care alone. The main goal was to see if…

This study tested a very short online therapy program to help pregnant women manage anxiety related to COVID-19. 69 pregnant women with anxiety took part in virtual group sessions. The goal was to see if the program was practical and well-liked, not to prove it works. Results wil…

This pilot study tested whether combining exercise with a gentle brain stimulation technique (transcranial direct current stimulation) could improve memory in 60 older adults with mild cognitive impairment or Alzheimer's disease. Participants exercised while receiving stimulation…

This study looked at how to best dose tranexamic acid (TXA), a drug that reduces bleeding, during hip or knee replacement surgery. Researchers tested two different dosing plans in 21 adults to see how the drug works in the body. The goal is to create clear dosing guidelines to lo…

This study tested whether a device that gives real-time feedback on breathing support can help paramedics improve care during out-of-hospital cardiac arrest. Researchers compared ventilation quality before and after using the Zoll Accuvent device in 412 adults. The goal was to se…

This study tested whether a special type of scan (FET-PET/MRI) can more accurately show the full extent of glioblastoma brain tumors after surgery. The goal was to see if this scan could help doctors plan radiation treatment better than standard MRI alone. Eleven adults who had s…