Stony Brook University

This study tests whether a 12-week group therapy program called Mom Power can help new mothers with opioid use disorder improve their mood, reduce stress, and strengthen the bond with their child. About 160 mothers with a child aged 5 or younger will be assigned to either the Mom…

This early-stage trial is testing whether combining a targeted radiation therapy with an immunotherapy drug (atezolizumab) before surgery can help fight glioblastoma, a fast-growing brain tumor. Twelve newly diagnosed patients will receive two weeks of treatment, then undergo sur…

This study aims to find better ways to treat depression in people with chronic kidney disease (CKD). About 201 adults with advanced CKD and major depression will receive either behavioral activation teletherapy plus a non-SSRI antidepressant, or the antidepressant plus teletherap…

This study compares intravenous famotidine (a stomach acid reducer) and oral antacids (like Maalox) for treating dyspepsia (stomach pain) in the emergency department. About 80 adults with upper abdominal pain will rate their pain every 15 minutes for an hour. The goal is to see w…

This study compares using a Foley balloon plus misoprostol versus standard osmotic dilators (Laminaria) to prepare the cervix before a second-trimester surgical abortion (16-21 weeks). About 102 women will take part to see if the balloon method is just as effective and leads to s…

This study tests whether a nerve block called an inter-semispinalis plane block can help people use fewer opioid painkillers after posterior cervical spine surgery. About 60 participants will be randomly assigned to receive either the nerve block plus standard pain medication or …

This early study tests whether a non-invasive device that gently stimulates a nerve in the ear (taVNS) is safe and practical for ICU patients with delirium—a state of confusion that can slow recovery. Ten right-handed adults with delirium will receive 30-minute sessions twice dai…

This study tests whether giving coloring activities (nature scenes, geometric shapes, word searches, or free drawing) to adults waiting in the emergency department can lower their self-reported pain and anxiety. Researchers will measure changes using standard questionnaires. If e…

This study tests a brief motivational program to increase physical activity in 84 cancer survivors who are part of the World Trade Center Health Program. The program combines counseling, a Fitbit to track steps, and personalized activity planning. The goal is to see if participan…

This study tests a new computer system called SeeMe that can detect tiny movements in people with severe traumatic brain injury (TBI). Current exams may miss these movements, leading to misdiagnosis. The study will involve 60-80 TBI patients and aims to see if SeeMe can find sign…

This study surveys 40 adults who have never had anesthesia before. They fill out a questionnaire before their low-risk surgery and answer follow-up questions a few days later. The goal is to see how their fear and anxiety change from before to after the experience. No drugs or tr…

This study looks at how two types of energy—glucose and ketones—change brain activity and behavior in people with bipolar disorder. Participants will have MRI scans while playing money-winning games, before and after drinking either glucose or ketones. Researchers will compare re…

This study looks at how cognitive behavioral therapy for insomnia (CBT-I) changes a specific brain receptor (mGluR5) in people with major depression. 42 adults with depression and insomnia will receive online CBT-I and undergo PET brain scans before and after treatment. The goal …

This study tests a decision aid for people with small thyroid nodules or early thyroid cancer. Participants get extra information to help them choose a treatment that matches their values. They fill out surveys about their satisfaction and decision-making process. The goal is to …