State University Of New York At Buffalo

This study tests whether adding two extra medications (semaglutide and dapagliflozin) to insulin helps adults with type 1 diabetes control their blood sugar better than insulin alone or with just one extra drug. The 78 participants, aged 18-70 with a BMI of 25 or higher, will be …

This study tests whether giving cash payments to inner-city African Americans with poorly controlled type 2 diabetes can improve their blood sugar levels and quality of life. Participants are randomly assigned to receive money for attending virtual diabetes education sessions or …

This study tests whether low-dose lithium can slow the progression of Parkinson's disease. About 35 people who have already completed a lithium study will take lithium for 24 more weeks. Researchers will use brain scans and blood tests to see if lithium affects disease-related ch…

This study tests whether adding financial rewards to nurse coaching and home monitoring helps people with type 2 diabetes improve their blood sugar control more than coaching and monitoring alone. About 450 adults with poorly controlled diabetes will be randomly assigned to one o…

This study tests a family-based weight management program for youth with type 1 diabetes (ages 6-17) who are overweight or obese, along with one parent who is also overweight. The program is adapted from a proven approach and delivered in a hybrid format. The goal is to improve w…

This study planned to test whether the antibiotic minocycline could improve recovery in people who had a severe stroke and underwent a procedure to remove the clot. Participants would have received minocycline or a placebo for 21 days. The study was withdrawn before any participa…

This study is creating a HIV prevention program designed by and for young women aged 18-35 in Ghana. It focuses on two proven tools: HIV self-testing and PrEP (a daily pill to prevent HIV). The program will be delivered through WhatsApp and community workshops, and researchers wi…

This study tests whether a community-based music mindfulness program can reduce anxiety and depression in children aged 8-12 with ADHD or anxiety. Participants attend bi-weekly sessions for 8 weeks, wear fitness trackers, and complete surveys. The goal is to see if this approach …

This study looks at two ways to manage pain from a recent muscle or bone injury: a steroid dose pack or a mix of Tylenol and Ibuprofen. About 60 adults with new injuries will take one of these treatments for 6 days. The goal is to see which method reduces pain and improves functi…

This study planned to see if a corn-starch drink taken before exercise could help teens with type 1 diabetes avoid low blood sugar (hypoglycemia) after working out. It would have involved about 20 teens biking while wearing a continuous glucose monitor. However, the study was wit…

This study looks at whether a group program combining visual art and exercise games can improve thinking, balance, and walking in older adults. About 80 participants with mild physical or cognitive issues will take part. The goal is to see if this fun, community-based approach he…

This study tests a 12-week program that teaches parents how to use positive, supportive feeding practices to help their children eat better and grow healthily. It includes 36 parents and their children aged 5-11 who are at risk for obesity. The program focuses on giving parents t…

This study looks at why some people avoid information about colorectal cancer and tests a video designed to help them engage with it instead. About 1,500 adults aged 45 to 75 who are not up-to-date on screening will watch either the special video or a neutral one. Researchers wil…

This study looks at people with rapid-onset dystonia-parkinsonism (RDP), a rare genetic movement disorder. Researchers aim to find how many people have the condition, track its symptoms over time, and understand its genetic causes. Participants undergo interviews and assessments …

This study looks at 302 people with heart disease and an implantable defibrillator (ICD) to see if a special PET scan can better predict who is at risk for sudden cardiac arrest. Currently, doctors mainly use a measure of heart pumping strength, but this research adds information…

This study compares doing clinical trial visits remotely (from home) versus in-person at a clinic. The goal is to see which method works better for getting people to join, stay in the study, and follow the treatment plan. About 200 adults will take part for 3 months, and the resu…

This study looks at whether giving women who struggle with food insecurity a steady, healthy meal plan can improve their metabolism and reduce cravings for unhealthy foods. Researchers will measure changes in weight, blood sugar, and how the body burns energy. The goal is to unde…