Sir Run Run Shaw Hospital

This study tests whether combining two procedures—closing the left atrial appendage and using pulsed field ablation to correct heart rhythm—works better than closing the appendage alone in people with persistent atrial fibrillation and high stroke risk. Fifty participants will be…

This Phase III trial tests whether a modified short-course radiation that spares nearby lymph nodes, combined with chemotherapy (CAPOX) and the immunotherapy drug tislelizumab, works better than standard radiation plus chemotherapy for people with a certain type of rectal cancer …

This early study tests a new device that uses electric pulses to destroy malignant lung nodules in people with early-stage lung cancer or limited lung metastases. Five participants will undergo a procedure where a needle is guided into the tumor using CT scans, then delivers elec…

This study tests a new treatment approach for people with advanced colorectal cancer that has spread to the liver, lungs, or abdomen and cannot be removed with surgery. The treatment combines a short course of radiation with immunotherapy (tislelizumab), chemotherapy (CAPOX), and…

This study tests whether using a handheld breathing device (OPEP) at home, combined with aerobic exercise, can reduce serious flare-ups and hospital visits in people with moderate to severe COPD. About 312 participants aged 40-80 will be split into four groups: standard care, OPE…

This study compares two ways of doing a heart procedure called catheter ablation for people with atrial fibrillation (an irregular heartbeat). One method uses X-rays to guide the doctor, and the other does not. The goal is to see if the no-X-ray method works just as well and is a…

This Phase 2 trial tests two immunotherapy drugs (iparomlimab and tuvonralimab) given before surgery to 29 patients with a specific genetic type of colorectal cancer (MSI-H/dMMR). The goal is to see if this combination can completely eliminate the tumor before surgery. Researcher…

This study is testing whether an artificial intelligence program can detect chronic obstructive pulmonary disease (COPD) by analyzing cough sounds recorded on a smartphone. Researchers will collect cough recordings and medical data from 3,000 adults in China, both with and withou…

This study tests a non-invasive ear stimulation technique (taVNS) to prevent acute kidney injury in 152 adults having heart surgery with a heart-lung machine. Half receive real stimulation before and after surgery; the other half get a sham. The main goal is to see if fewer peopl…