Shanghai 10th People's Hospital

This study tests whether Coenzyme I injections can reverse vascular aging in 60 adults aged 40-70 with stiff arteries. Participants receive either the coenzyme or a placebo, and researchers measure changes in blood vessel function and stiffness over 28 days. The goal is to see if…

This study tests whether adding a fecal microbiota transplant (FMT) from a healthy donor to standard chemotherapy can shrink tumors in people with advanced colorectal cancer that cannot be removed by surgery. About 220 participants will be randomly assigned to receive either stan…

This study tests a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to see if it safely lowers diastolic blood pressure (the bottom number) in people with high diastolic pressure who are not on medication. About 124 adults will be ra…

This study looks at whether the drug guselkumab can stop Crohn's disease from coming back after bowel surgery. About 88 adults with moderate to severe Crohn's who have had surgery will receive guselkumab and be monitored for up to 48 weeks. The main goal is to see if the disease …

This early-stage trial tests a new treatment using a patient's own immune cells (γδ-T cells) to fight advanced bladder cancer that hasn't responded to standard therapies. About 20 participants will receive multiple infusions of these cells. The goal is to control tumor growth and…

This early-stage study tests a drug called romiplostim N01 in 280 adults with sepsis and very low platelet counts. The goal is to see if it can safely raise platelet levels faster than standard treatment, potentially reducing ICU stays and costs. Participants are randomly assigne…

This study looks at a new, fast test called NuRapid-CRISPR that can quickly find the germ causing sepsis in ICU patients. The goal is to see if using this test to guide treatment can lower the number of deaths within 28 days compared to the usual slower culture method. About 396 …