Shandong Suncadia Medicine Co., Ltd.

This study compares a new drug, HRS-7535, to an existing diabetes medication, dapagliflozin, in adults with type 2 diabetes whose blood sugar is not well controlled with metformin alone. The goal is to see if HRS-7535 works better at lowering blood sugar and body weight over 32 w…

This completed phase 3 trial tested three doses of the oral drug HRS-7535 against a placebo in 284 adults with type 2 diabetes whose blood sugar was not well controlled by diet and exercise alone. The main goal was to see if HRS-7535 could lower HbA1c (a measure of average blood …

This phase 2 trial tested HRS-7535, a new drug, in 281 adults with type 2 diabetes and diabetic kidney disease. Participants received either the drug or a placebo for 16 weeks. The main goal was to see if HRS-7535 could reduce protein in the urine, a sign of kidney damage, and he…

This early-stage study tested a new drug called HRS-1301 in 82 healthy adults to check its safety and how the body processes it. The goal is to see if it can help control high cholesterol. Participants received either the drug or a placebo, and researchers monitored for side effe…

This Phase 2 trial tested a new drug called HRS-7535 in 155 adults with type 2 diabetes whose blood sugar was not well controlled despite taking metformin and an SGLT2i. Participants received either HRS-7535 or a placebo for 16 weeks. The main goal was to see if the drug could lo…

This completed Phase 2 trial tested two drugs, HRS-1780 and henagliflozin, in 181 adults with chronic kidney disease. Participants took the drugs or placebos for 13 weeks to see if the drugs could reduce protein in the urine, a sign of kidney damage. The study aimed to find a new…

This study looked at the long-term safety and effectiveness of the drug HRS-7535 for weight management in 81 adults with obesity who had already completed a 36-week treatment course. Participants took the drug for an additional 32 weeks to see how well it helped maintain weight l…

This Phase 2 trial tested an oral drug called HRS-5346 in 120 adults with high lipoprotein(a) levels and a high risk of cardiovascular events. The main goal was to see how well the drug lowers Lp(a) levels compared to a placebo, and to check its safety. The study is completed, an…

This study tested a new medicine called HRS-2129 to see if it safely reduces pain after orthopedic surgery (like bone or joint procedures). About 199 adults took part. Researchers measured pain levels over time and checked for side effects to find the best dose.

This completed Phase 1 study tested the safety and tolerability of HRS-2129, a new drug for pain, in 23 healthy adults aged 18 to 55. Researchers measured side effects and how the body processes the drug, along with pain responses to cold and heat. Because it was only in healthy …

This Phase 1 study in 40 overweight or obese adults examined how a new drug called HRS-7535 interacts with four common medications: acetaminophen (pain reliever), digoxin (heart medication), rosuvastatin (cholesterol drug), and omeprazole (acid reflux treatment). Participants too…

This study looked at how the body absorbs, breaks down, and gets rid of a new breast cancer medicine called HRS-8080. Six healthy postmenopausal women took a single dose of the drug with a radioactive tag so researchers could track it. The goal was to understand the drug's path t…

This early-phase study tested the drug HRS-8080 in 24 healthy adults to see how well it is absorbed and whether food changes its levels in the body. Participants took single doses under different conditions, including fasting and with low- or high-fat meals. The results will help…

This early-stage study looked at how two different tablet versions of the experimental diabetes drug HRS-7535 are absorbed in the body, and whether food changes that. It involved 24 healthy adults who took the tablets under fasting and fed conditions. The goal was to compare the …

This study looked at how two drugs, metformin and HRS-7535, behave in the bodies of 18 healthy men aged 18-50. The goal was to measure drug levels and safety, not to treat any disease. Results will help guide future diabetes research.

This completed Phase 1 trial tested how four diabetes medications (HRS-1780, henagliflozin, metformin, and HRS-7535) affect each other's levels in the body. Twenty-four healthy men took the drugs in a fixed order, and researchers measured drug concentrations and side effects. The…

This study looked at how the body absorbs a new drug called HRS-1893, which is being developed for heart muscle disease (cardiomyopathy). 38 healthy adults took different versions of the tablet, with and without food, to see which form works best and if food changes how much drug…

This study looked at how the experimental diabetes drug HRS-7535 behaves in people with mild or moderate liver impairment compared to those with normal liver function. Twenty-four adults completed the trial, which measured drug levels in the blood and checked for side effects. Th…

This study looked at how a common antifungal drug (itraconazole) changes the way the body handles a new experimental breast cancer drug (HRS-8080). Sixteen healthy adults took HRS-8080 alone and then with itraconazole to measure drug levels and safety. The goal was to gather info…

This study looked at how a new drug called HRS-1301 changes the way the body processes rosuvastatin, a common cholesterol-lowering medication. Sixteen healthy adults took both drugs so researchers could measure drug levels in the blood. The goal was purely to gather information, …

This completed Phase 1 study looked at how HRS-1893 tablets are processed in people with mild or moderate kidney impairment compared to healthy subjects. The goal was to understand dosing needs for patients with hypertrophic cardiomyopathy who also have kidney issues. Twenty-four…