New drug HRS-7535 aims to protect kidneys in diabetes patients

NCT ID NCT06415214

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tested HRS-7535, a new drug, in 281 adults with type 2 diabetes and diabetic kidney disease. Participants received either the drug or a placebo for 16 weeks. The main goal was to see if HRS-7535 could reduce protein in the urine, a sign of kidney damage, and help preserve kidney function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HRS-7535

What this could lead to

If it works, HRS-7535 could offer a new way to slow kidney damage in people with type 2 diabetes, potentially reducing the need for dialysis or transplant.

What could go wrong

This is an early phase 2 trial with only 281 participants, so results may not apply to everyone. The drug may not improve kidney function or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetic kidney disease type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital, College of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310003, China