Rhythm Pharmaceuticals, Inc.

This study is testing whether a daily injection called setmelanotide can help people with Prader-Willi Syndrome manage their weight and reduce extreme hunger behaviors. About 20 participants aged 6-65 will receive the medication for up to one year while researchers monitor safety…

This study is testing whether the drug setmelanotide can help people with obesity caused by specific rare genetic changes lose weight. About 300 participants, aged 6 to 65, with one of these genetic variants will receive either the drug or a placebo for comparison. The main goal …

This study continues testing an experimental drug called bivamelagon for people with obesity caused by damage to a specific brain area (hypothalamus). It follows 25 participants for up to 2 years to check long-term safety and see if the drug helps control weight and improve quali…

This study continues testing setmelanotide, a medication for rare genetic obesity conditions, to check its long-term safety. It includes patients aged 2 and older who benefited from the drug in earlier trials. The main goal is to monitor side effects over an extended treatment pe…