New hope for rare obesity: setmelanotide safety trial expands

NCT ID NCT06596135

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This study looks at the long-term safety of a drug called setmelanotide in people aged 2 and older with rare genetic obesity. Participants must have already been in a setmelanotide study and shown benefit. The goal is to monitor side effects over time.

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Contacts and locations

Locations

  • Children's Minnesota

    Saint Paul, Minnesota, 55102, United States

  • Geisinger Health System

    Danville, Pennsylvania, 17821, United States

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85258, United States

  • M3 Wake Research, Inc

    Raleigh, North Carolina, 27612, United States

  • Marshfield Clinical Research Institute

    Marshfield, Wisconsin, 54449, United States

  • Mayo Clinic - Rochester

    Rochester, Minnesota, 55905, United States

  • Seattle Children's Research Institute

    Seattle, Washington, 98105, United States

  • UC San Diego- Rady Children's Hospital

    San Diego, California, 92123, United States

  • University of Buffalo

    Getzville, New York, 14068, United States

  • University of Florida at Gainesville

    Gainesville, Florida, 32611, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • Vanderbilt University School of Medicine

    Nashville, Tennessee, 37232, United States

  • WR-ClinSearch

    Chattanooga, Tennessee, 37421, United States

Conditions

Explore the condition pages connected to this study.