Philipps University Marburg

This study tests a new way of caring for people with new-onset stable chest pain who may have coronary artery disease. Instead of routinely using a heart catheterization, the new model promotes a less invasive CT scan first. About 3,369 adults across 16 regions in Germany will ta…

This study compares two new group therapies for adults with major depression. One therapy helps change rigid negative thoughts, while the other boosts sensitivity to positive experiences. 150 participants will be randomly assigned to one of the therapies or a waiting list, and th…

This study tests whether adding a guided imagery exercise after a virtual reality (VR) speech practice session helps people with public speaking anxiety feel less fearful in new situations. About 48 adults with high speech anxiety will do one VR speech session, then either mental…

This study tests whether enoxolone, a compound from licorice, can improve depression symptoms in people with unipolar depression. Researchers will check if certain biological markers (like hormone levels and blood pressure) predict who responds better to enoxolone versus a placeb…

This study looks at whether adding a positive mental rehearsal step after a single session of exposure therapy can improve symptoms of social anxiety. About 40 adults with high social anxiety will take part. After facing a feared social situation, half will practice replaying the…

This study tests whether a simple mental exercise—imagining yourself approaching a feared social situation—can increase motivation and pleasure in people with social anxiety. About 58 participants will learn about anxiety and then either practice mental imagery or a verbal reason…