Licorice root extract shows promise for Hard-to-Treat depression

NCT ID NCT05570110

First seen Jan 08, 2026 · Last updated May 14, 2026 · Updated 19 times

Summary

This study tests whether enoxolone, a compound from licorice, can improve depression symptoms in people with unipolar depression. Researchers will check if certain biological markers (like hormone levels and blood pressure) predict who responds better to enoxolone versus a placebo. About 80 adults will take part, and the goal is to see if enoxolone eases depression and changes those markers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinic for Psychiatry and Psychotherapy

    RECRUITING

    Marburg, Hesse, 35039, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.