Peking University

This phase 3 trial compares a new drug called Retlirafusp alfa plus chemotherapy against standard immunotherapy plus chemotherapy for people with advanced stomach or gastroesophageal junction cancer that has spread to the liver and has not been treated before. The study aims to s…

This early-stage trial tests a new biologic drug, SIG001, in 66 people with advanced solid tumors. The main goals are to check safety, find the right dose, and see how the drug behaves in the body. Participants receive SIG001 intravenously every two weeks and are monitored for si…

This early-phase study tests a new drug combination (PX plus nab-paclitaxel) given directly into the abdomen for people with a type of advanced cancer that has spread to the lining of the belly. The main goal is to find a safe dose and check for side effects. About 22 adults with…

This study tests a new approach to managing type 2 diabetes that combines an AI smartphone app with support from family doctors. About 1200 adults in China will use the app to track their meals and get personalized feedback, while also receiving regular check-ins from their docto…

This study tests a school-based weight management program using a WeChat digital platform to help children in Fangshan District, Beijing, avoid excessive weight gain. About 1,400 children in grades 2 and 3 will either receive the program (health classes, daily physical activity, …

This study tests a digital health program that uses patient data to identify pregnant women at high risk for gestational diabetes. High-risk participants will receive online education, lifestyle coaching, and self-management tools to prevent the condition. The goal is to reduce d…

This study tests whether using a low-sodium salt substitute instead of regular salt can lower blood pressure and prevent pregnancy-related high blood pressure disorders in women at high risk. About 3,200 pregnant women in China will be randomly assigned to use either the salt sub…

This study compares two injection sites for Botox to treat drooping mouth corners, a common sign of aging. 266 adults aged 18-60 will receive a single injection either in the upper or lower part of a specific mouth muscle. The goal is to see which spot works better and safer, and…

This study tests whether an AI-assisted writing program can help Chinese teenagers (ages 10-19) who are struggling with prolonged grief after losing a loved one. Participants will complete three guided writing sessions over six days, with some receiving personalized AI feedback. …

This study looks at how well and safely the antidepressant escitalopram works in people experiencing their first episode of major depression who have never taken medication for it. Two hundred adults aged 18 to 65 will take escitalopram for 8 weeks, and researchers will track the…

This study will test whether different amounts of computerized brain training can improve thinking and memory in older adults with mild cognitive impairment. About 234 people aged 60 and older will be assigned to one of several training schedules over 12 weeks. Researchers will t…

This study looks at how people with slightly high blood pressure react to salt. Participants will eat both high-salt and low-salt meals to see if their blood pressure changes. The goal is to find out who is salt-sensitive and who is not. No new treatments are tested—just careful …