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Timing your meals or halving your rice: a new trial tests simple diet hacks for weight loss and blood sugar control

NCT ID NCT07726615

Disease control Sponsor: Peking University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial compares two simple diet strategies — eating only during early hours or cutting staple foods like rice and bread in half — each combined with an app-guided exercise program, against exercise alone. Researchers want to see which approach helps adults with obesity and prediabetes lose more weight and improve blood sugar over 12 weeks. Three hundred participants in China will be randomly assigned to one of the three groups.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a combination of early time-restricted eating, staple food reduction, and app-supported exercise
What this could lead to
If effective, these lifestyle strategies could offer simple, scalable ways to manage weight and blood sugar in people with obesity and prediabetes.
What could go wrong
This is a 12-week behavioral intervention with a 12-week follow-up — long-term effects are unknown. Adherence to diet and exercise may vary, and results may not apply to older adults or other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 50 years, all sexes. * Body mass index (BMI) \>=28 kg/m2. * Willing and able to comply with study procedures and provide written informed consent. * Resident living near a participating study site and able to complete scheduled visits. * No habitual time-restricted eating or other fasting regimen, such as alternate-day fasting or fasting-mimicking diet. * Abnormal glucose metabolism or diabetes, defined as fasting plasma glucose \>5.6 mmol/L or HbA1c \>5.7%. Exclusion Criteria: * Secondary obesity, such as hypothyroidism or Cushing syndrome. * Use of weight-loss medication within 90 days before screening, or body weight change \>5 kg within 90 days before screening. * Pregnant, lactating, or planning pregnancy during the study period. * Severe cardiac, hepatic, or renal dysfunction. * Severe psychiatric disease or cognitive impairment that prevents cooperation with the study. * Contraindication to exercise, such as severe osteoarthritis. * Unable or unwilling to follow the study diet and exercise intervention. * Long-term use of medications that may significantly affect body weight. * Active malignancy in any organ system. * Any other condition that, in the investigator's judgment, may affect efficacy or safety evaluation or make the participant unsuitable for the study.

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Conditions

The condition(s) this trial relates to.

Intermittent Fasting Obesity obesity disorder prediabetes syndrome type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity; impaired glucose regulation; prediabetes; type 2 diabetes mellitus

How to take part

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  1. The official record

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