Orthocarolina Research Institute, Inc.

This study tests whether giving antibiotics directly into the bone during surgery can better control infections in artificial joints. About 100 adults with infected knee or hip replacements will receive this treatment. The goal is to reduce the chance of infection coming back and…

This study tests whether a special brain rehabilitation program, done before and after a major amputation, can prevent or lessen phantom limb pain. About 50 people aged 13 and older who are having an amputation will use virtual reality daily while in the hospital. Researchers wil…

This study compares two different pain pump devices used after total knee replacement to see which one works better with standard pain management. About 65 adults having knee surgery will be randomly assigned to receive either standard care alone or standard care plus one of two …

This study tests whether a pain management plan without opioids works as well as one with opioids for teens having scoliosis surgery. About 58 patients aged 10-20 will be enrolled. The goal is to see if the opioid-free approach can control pain just as well while reducing opioid …