Orthocarolina Research Institute, Inc.

This study tests whether giving antibiotics directly into the bone during a standard cleaning surgery can better control joint infections and reduce the need for additional major surgeries. About 100 adults with infected knee or hip replacements will receive this targeted antibio…

This study tests whether a special brain rehabilitation program, done before and after a major amputation, can prevent or lessen phantom limb pain. About 50 people aged 13 and older who are having an amputation will use virtual reality daily while in the hospital. Researchers wil…

This study compares two types of pain-relief pumps placed inside the knee joint after total knee replacement. 65 adults having outpatient knee surgery will be randomly assigned to receive either standard pain management or one of two pump brands. The goal is to see which approach…

This study compares a new opioid-free pain management plan to the usual opioid-based approach for teenagers (ages 10-20) having spinal fusion surgery for scoliosis. The opioid-free plan uses a mix of numbing injections and non-opioid medications like gabapentin, ibuprofen, and ac…