Orthocarolina Research Institute, Inc.
Clinical trials sponsored by Orthocarolina Research Institute, Inc., explained in plain language.
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New blood test could tell if your metal hip needs replacing
Diagnosis TerminatedThis study aimed to develop a blood and joint fluid test to detect tissue death (necrosis) caused by metal-on-metal hip replacements. Researchers enrolled 174 hip patients, including those needing revision surgery and a control group. The goal was to create a diagnostic tool to h…
Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Diagnosis
Last updated Jun 17, 2026 12:05 UTC
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Knee replacement pain study seeks best relief combo
Symptom relief TerminatedThis study looked at whether adding a nerve block (adductor canal block) to a standard pain injection around the knee provides extra pain relief for people having total knee replacement. About 93 adults with osteoarthritis participated. The goal was to find the best way to manage…
Phase: PHASE2, PHASE3 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 11, 2026 12:09 UTC
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Spine surgery pain study halted early: which method works best?
Symptom relief TerminatedThis study aimed to see if a combination of pain medicines (multimodal analgesia) works better than standard care for pain after lower back fusion surgery. It included 50 adults aged 18 to 70. The study was stopped early, so results are limited.
Phase: PHASE4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 10, 2026 13:25 UTC
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Tiny ACL study halted: did tourniquets cause more pain?
Knowledge-focused TerminatedThis study aimed to see if limiting tourniquet use during ACL knee surgery would reduce pain and help patients regain leg muscle strength faster. Only one person was enrolled before the study was stopped early. The results are not available, so no conclusions can be drawn.
Phase: NA • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:53 UTC