Ocuphire Pharma, Inc.

This study tested an oral medication called APX3330 in 103 adults with moderate to severe diabetic retinopathy, a leading cause of vision loss. The pill aims to reduce inflammation and low-oxygen stress in the eye. Researchers measured whether the drug could improve the severity …

This completed Phase 3 trial tested whether phentolamine eye drops (Nyxol) can improve near vision in people with presbyopia, the age-related loss of ability to focus on close objects. 569 adults aged 45 to 64 used the drops or a placebo once daily for 8 days. The main goal was t…

This Phase 3 trial tested Nyxol eye drops, alone or with low-dose pilocarpine, in 333 adults aged 40–64 with presbyopia (age-related difficulty seeing up close). The goal was to improve near vision without losing distance vision. Participants received drops and were measured afte…

This study tested an eye drop (POS) in 200 adults who had poor night vision after LASIK or similar eye surgery. The goal was to see if the drops could help them see better in dim light, reducing problems like glare and halos. Participants used the drops for 15 days and had their …

This study tested whether Nyxol eye drops can help people who have trouble seeing in dim light, often after eye surgeries like LASIK or cataract surgery. 144 adults received either the eye drops or a placebo for 8 days. The main goal was to see if Nyxol could improve vision in lo…

This study tested whether a combination of two eye drops (Nyxol and pilocarpine) can help people with presbyopia—age-related difficulty seeing up close—read better without glasses. About 150 adults aged 40 to 64 took part. The main goal was to see how many people could read 15 or…