New eye drops aim to sharpen night vision

NCT ID NCT04638660

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 32 times

Summary

This study tested an eye drop called Nyxol in 144 adults who have trouble seeing in dim light, often after eye surgeries like cataract or LASIK. The goal was to see if Nyxol could improve how well they read letters on a low-contrast chart in dim conditions. Participants used the drops or a placebo for 8 days, and researchers measured vision improvements and safety.

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Contacts and locations

Locations

  • Clinical Site 1

    Petaluma, California, 94954, United States

  • Clinical Site 10

    Palisades Park, New Jersey, 07650, United States

  • Clinical Site 11

    Memphis, Tennessee, 38119, United States

  • Clinical Site 13

    Pittsburg, Kansas, 66762, United States

  • Clinical Site 14

    Louisville, Kentucky, 41008, United States

  • Clinical Site 18

    Jacksonville, Florida, 32256, United States

  • Clinical Site 19

    Ogden, Utah, 84403, United States

  • Clinical Site 2

    Fargo, North Dakota, 58103, United States

  • Clinical Site 20

    Edgewood, Kentucky, 41017, United States

  • Clinical Site 22

    High Point, North Carolina, 27262, United States

  • Clinical Site 3

    Jacksonville, Florida, 32204, United States

  • Clinical Site 4

    Elizabeth City, North Carolina, 27909, United States

  • Clinical Site 5

    San Antonio, Texas, 78240, United States

  • Clinical Site 6

    Newport Beach, California, 92663, United States

  • Clinical Site 8

    Pennington, New Jersey, 08534, United States

  • Clinical Site 9

    High Point, North Carolina, 27262, United States

  • Clinical Test 15

    Warwick, Rhode Island, 57108, United States

Conditions

Explore the condition pages connected to this study.