Northwestern University

This study is for people with liver cancer whose liver is too small for surgery. Doctors use a special radiation treatment (Y90) to help the healthy part of the liver grow larger. Once it's big enough, patients can have surgery to remove the cancer. The study tests different radi…

This study tests the safety and effectiveness of Ublituximab (Briumvi) given twice a year for early relapsing multiple sclerosis. About 40 adults with mild disability will receive the drug and be monitored for about a year. Researchers will measure nerve damage markers in the blo…

This study tests a new type of proton radiation called P-SFRT for people with a rare cancer called retroperitoneal sarcoma. The treatment delivers high doses of radiation to the tumor while protecting nearby organs. The goal is to find the best dose and see if it improves tumor s…

This study tests a drug called zanzalintinib (XL092) in 29 people with advanced leiomyosarcoma that has spread or cannot be removed by surgery. The drug works by blocking signals that help cancer cells grow. The goal is to see if it can slow the cancer's progression and improve s…

This study tests a wearable device called a myoelectric-computer interface (MCI) that helps stroke survivors improve arm movement. The device works by giving feedback on muscle activity to reduce abnormal co-activation that limits coordination. The study will enroll 96 people who…

This study tests whether an online program that teaches positive emotion skills can improve mental well-being and slow biological aging. Researchers will measure changes in mood, purpose, and biological age markers in 80 adults aged 40-70 living in the Chicago area. The program i…

This study is creating a large collection of blood, skin, and spinal fluid samples along with health information from 2,500 adults with neuromuscular diseases (like ALS, neuropathy, and muscular dystrophy). The goal is to help researchers better understand these conditions and de…

This study tests whether a special MRI can safely and accurately monitor heart transplant patients for complications like rejection and blood vessel disease. Current monitoring often requires invasive biopsies and catheter procedures. The goal is to see if MRI can replace these t…

This study enrolls 222 men with low- to intermediate-risk prostate cancer to see if adding MRI and a genetic test helps them stick with active surveillance (monitoring the cancer instead of treating it right away). The goal is to improve safety and reduce unnecessary biopsies and…

This study looks for better ways to monitor kidney transplant recipients for problems like rejection or scarring. Researchers will collect blood, urine, and tissue samples from 1000 adults during routine biopsies to find early warning signs. The goal is to develop less invasive t…

This study looks at how the brain's noradrenaline system is linked to sleep and thinking skills in older adults with insomnia. Researchers will measure brain chemicals and use light therapy to see if improving daytime alertness can help sleep and memory. The goal is to understand…