Nichd Neonatal Research Network

This study compares two ways of using phototherapy (light treatment) for jaundice in extremely premature infants (under 750 grams or 27 weeks gestation). One group gets continuous light, the other gets timed cycles based on bilirubin levels. The main goal is to see if cycled phot…

This study looks at whether actively treating a heart condition called patent ductus arteriosus (PDA) in premature babies is better than simply monitoring it. About 482 infants born between 22 and 28 weeks of pregnancy will be followed to see which approach reduces the risk of de…

This Phase 3 trial tests whether adding budesonide (an anti-inflammatory) to standard surfactant treatment helps extremely preterm babies avoid chronic lung disease or death. About 642 infants born before 29 weeks or weighing under 1000 grams will receive either the combo or surf…