Neurocrine Biosciences

This study tested an experimental drug called NBI-827104 in 24 children with a rare form of epilepsy that causes constant brain activity during sleep. The goal was to see if the drug could reduce abnormal brain waves and improve safety. The trial was double-blind, meaning neither…

This study tested whether the drug valbenazine can reduce chorea (uncontrolled, jerky movements) in children and adults with cerebral palsy. 86 participants received either valbenazine or a placebo for 14 weeks. The goal was to see if the drug improves movement control and overal…

This study tested whether adding valbenazine to standard antipsychotic medication helps reduce schizophrenia symptoms in adults who did not respond well to treatment alone. Over 400 participants took either valbenazine or a placebo for 10 weeks. The main goal was to see if valben…

This study looked at how well valbenazine works for tardive dyskinesia, a condition causing uncontrollable movements often linked to psychiatric medications. Fifty-nine adults with schizophrenia, bipolar disorder, or major depression took valbenazine for up to 24 weeks. Researche…

This study tested an experimental drug called NBI-1070770 in 73 adults with major depressive disorder. The goal was to see if it could safely and quickly improve depression symptoms compared to a placebo. Participants continued their usual antidepressants during the trial.