New depression drug shows promise in early trial

NCT ID NCT06267846

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 28 times

Summary

This study tested an experimental drug called NBI-1070770 in 73 adults with major depressive disorder. The goal was to see if it could safely and quickly improve depression symptoms compared to a placebo. Participants continued their usual antidepressants during the trial.

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Contacts and locations

Locations

  • Neurocrine Clinical Site

    Little Rock, Arkansas, 72211, United States

  • Neurocrine Clinical Site

    Rogers, Arkansas, 72758, United States

  • Neurocrine Clinical Site

    Lemon Grove, California, 91945, United States

  • Neurocrine Clinical Site

    Long Beach, California, 90806, United States

  • Neurocrine Clinical Site

    Hollywood, Florida, 33024, United States

  • Neurocrine Clinical Site

    Maitland, Florida, 32751, United States

  • Neurocrine Clinical Site

    Decatur, Georgia, 30030, United States

  • Neurocrine Clinical Site

    Savannah, Georgia, 31405, United States

  • Neurocrine Clinical Site

    Gaithersburg, Maryland, 20877, United States

  • Neurocrine Clinical Site

    Dayton, Ohio, 45439, United States

  • Neurocrine Clinical Site

    North Canton, Ohio, 44730, United States

  • Neurocrine Clinical Site

    Houston, Texas, 77008, United States

  • Neurocrine Clinical Site

    Richardson, Texas, 75080, United States

Conditions

Explore the condition pages connected to this study.