New hope for kids with rare Sleep-Related epilepsy?

NCT ID NCT04625101

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 33 times

Summary

This study tested an experimental drug called NBI-827104 in 24 children with a rare form of epilepsy that causes constant brain activity during sleep. The goal was to see if the drug could reduce abnormal brain waves and improve safety. The trial was double-blind, meaning neither the families nor the doctors knew who got the real drug or a placebo. Results will help determine if further testing is warranted.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Neurocrine Clinical Site

    Orange, California, 92868, United States

  • Neurocrine Clinical Site

    Aurora, Colorado, 80045, United States

  • Neurocrine Clinical Site

    Washington D.C., District of Columbia, 20010, United States

  • Neurocrine Clinical Site

    Miami, Florida, 33155, United States

  • Neurocrine Clinical Site

    Rochester, Minnesota, 55905, United States

  • Neurocrine Clinical Site

    Durham, North Carolina, 27710, United States

  • Neurocrine Clinical Site

    Cleveland, Ohio, 44195, United States

  • Neurocrine Clinical Site

    Philadelphia, Pennsylvania, 19104, United States

  • Neurocrine Clinical Site

    Calgary, Alberta, T3B 6A8, Canada

  • Neurocrine Clinical Site

    Dianalund, 4293, Denmark

  • Neurocrine Clinical Site

    Barcelona, 08950, Spain

  • Neurocrine Clinical Site

    Madrid, 28034, Spain

  • Neurocrine Clinical Site

    Basel, 4031, Switzerland

  • Neurocrine Clinical Site

    Zurich, 8032, Switzerland

  • Neurocrine Clinical Site

    London, WC1N 3JH, United Kingdom

Conditions

Explore the condition pages connected to this study.