Neurocrine Biosciences

This study is testing whether adding an investigational drug called NBI-1065845 to a person's current antidepressant medication can help reduce symptoms of major depressive disorder. It is for adults who have not gotten enough relief from their standard antidepressants alone. Par…

This study is testing whether adding an investigational drug called NBI-1065845 to a person's current antidepressant medication helps reduce depression symptoms more effectively. It's for adults with moderate-to-severe major depression who haven't gotten enough relief from their …

This study is testing whether an investigational medicine called NBI-1117568 can help reduce the severe symptoms of schizophrenia in adults who need to be hospitalized. Researchers will compare the drug to a placebo (an inactive substance) over 5 weeks. The goal is to see if the …

This study is testing the long-term safety of an investigational medication called NBI-1117568 for adults with schizophrenia. The trial will enroll 800 participants worldwide to monitor side effects and how well people tolerate the drug over an extended period. This is an open-la…

This study is testing whether an investigational medicine called NBI-1117568 can help reduce symptoms in adults with schizophrenia who need to be hospitalized. Researchers will compare the medicine against a placebo (inactive treatment) in 284 participants worldwide. The main goa…

This study is testing whether a new investigational medicine called NBI-1117568 can help reduce severe manic symptoms in adults with bipolar I disorder who are currently hospitalized for a manic episode. The trial will compare the medicine to a placebo (an inactive substance) in …

This study is testing a drug called crinecerfont in babies under 2 years old who have congenital adrenal hyperplasia (CAH), a rare genetic hormone condition. The main goal is to see how the baby's body processes the drug and to check if it is safe and well-tolerated. It is a smal…

This study is testing a medication called valbenazine for people with tardive dyskinesia (TD), which causes uncontrollable movements. It is for adults with TD who still have symptoms while taking a similar medication or after stopping one. The main goal is to see if switching to …

This study is testing whether adding an investigational drug called NBI-1065845 to standard antidepressant medication helps people with major depression who haven't gotten enough relief from their current treatment. It will involve about 200 adults with moderate to severe depress…

This study is testing if an investigational medicine called NBI-1065845 can help prevent depression symptoms from returning in people with major depressive disorder. It is for adults who are already taking standard antidepressants but still have significant symptoms. The main goa…