New schizophrenia drug shows promise in early trial

NCT ID NCT07288333

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called NBI-1117570 in 120 adults with schizophrenia who need hospital care. The goal is to see if it improves symptoms like hallucinations and disorganized thinking better than a placebo. Participants take the drug or a placebo daily for 35 days, and researchers measure changes using a standard symptom scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NBI-1117570

What this could lead to

If it works, this could point toward a new treatment option for schizophrenia that helps control symptoms during acute episodes.

What could go wrong

This is an early Phase 2a trial with only 120 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Neurocrine Clinical Site

    RECRUITING

    Kazanlak, 6100, Bulgaria

  • Neurocrine Clinical Site

    RECRUITING

    Pazardzhik, 4400, Bulgaria

  • Neurocrine Clinical Site

    RECRUITING

    Targovishte, 7700, Bulgaria

  • Neurocrine Clinical Site

    RECRUITING

    London, SE5 8AZ, United Kingdom

  • Neurocrine Clinical Site

    RECRUITING

    Oxford, OX3 7JX, United Kingdom