New schizophrenia pill aims to keep symptoms at bay

NCT ID NCT07227818

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether the experimental drug NBI-1117568 can delay relapse of schizophrenia symptoms compared to a placebo. About 560 adults with stable schizophrenia will first receive the drug openly, then be randomly assigned to continue it or switch to placebo. The main goal is to see how long it takes for symptoms to return.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NBI-1117568 (oral capsules)

What this could lead to

If successful, this could provide a new treatment option to help people with schizophrenia maintain stability and prevent symptom relapse.

What could go wrong

This is an early Phase 3 study, so results are not yet proven. The drug may not work better than placebo, and side effects are still being evaluated.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Neurocrine Clinical Site

    RECRUITING

    Garden Grove, California, 92845, United States

  • Neurocrine Clinical Site

    RECRUITING

    La Habra, California, 90631, United States

  • Neurocrine Clinical Site

    RECRUITING

    Lemon Grove, California, 91945, United States

  • Neurocrine Clinical Site

    RECRUITING

    Oceanside, California, 92056, United States

  • Neurocrine Clinical Site

    RECRUITING

    Torrance, California, 90504, United States

  • Neurocrine Clinical Site

    RECRUITING

    West Hills, California, 91307, United States

  • Neurocrine Clinical Site

    RECRUITING

    Hollywood, Florida, 33024, United States

  • Neurocrine Clinical Site

    RECRUITING

    Maitland, Florida, 32751, United States

  • Neurocrine Clinical Site

    RECRUITING

    Miami, Florida, 33122, United States

  • Neurocrine Clinical Site

    RECRUITING

    Miami, Florida, 33155, United States

  • Neurocrine Clinical Site

    RECRUITING

    Tampa, Florida, 33629, United States

  • Neurocrine Clinical Site

    RECRUITING

    West Palm Beach, Florida, 33024, United States

  • Neurocrine Clinical Site

    RECRUITING

    Atlanta, Georgia, 30318, United States

  • Neurocrine Clinical Site

    RECRUITING

    Boston, Massachusetts, 02116, United States

  • Neurocrine Clinical Site

    RECRUITING

    Flowood, Mississippi, 39232, United States

  • Neurocrine Clinical Site

    RECRUITING

    Cedarhurst, New York, 11516, United States

  • Neurocrine Clinical Site

    RECRUITING

    New York, New York, 10029, United States

  • Neurocrine Clinical Site

    RECRUITING

    New York, New York, 10036, United States

  • Neurocrine Clinical Site

    RECRUITING

    The Bronx, New York, 10461, United States

  • Neurocrine Clinical Site

    RECRUITING

    Bellevue, Washington, 98007, United States