National Institute Of Neurological Disorders And Stroke (ninds)

This study tests if deep brain stimulation (DBS) can help people with severe focal hand dystonia, a condition causing uncontrollable muscle contractions in the hand. Five adults who haven't improved with botulinum toxin will undergo surgery to implant a device that sends electric…

This early-stage study tests a drug called acamprosate in 30 people with ALS who have a specific genetic change (C9orf72). The main goal is to see if the drug is safe and to check for any signs it might slow the disease. Participants take the pill three times a day for 24 weeks a…

This study tests whether a treatment called IVIG (human immunoglobulin) can help with ongoing neurological symptoms like dizziness, memory problems, and weakness in people with Long COVID. About 45 adults who had COVID-19 at least 12 weeks ago will receive either IVIG or a placeb…

This study follows 250 people with von Hippel-Lindau (VHL) disease, ages 8 to 75, to track how brain and spinal cord tumors grow over 5 years. Researchers use regular MRI scans and blood tests to see what factors, like hormones, might affect tumor growth. The goal is to help doct…

This study aims to improve how doctors test for chronic autonomic failure, a condition where the body's automatic functions like blood pressure control don't work properly. It includes people with Parkinson's disease, multiple system atrophy, or related issues. Participants under…

This long-term study looks at people with inherited nerve and muscle disorders that start in childhood, along with their family members and healthy volunteers. The goal is to better understand how these diseases progress and to find better ways to measure changes over time. Parti…

This study looks at how the brain forms and retrieves memories by recording brain cell activity in people with epilepsy who are already having brain surgery. Up to 200 adults aged 18-65 will play memory games on a laptop while their brain activity is monitored. The goal is to fin…

This study follows 180 adults with syringomyelia (a fluid-filled cyst in the spinal cord) or related conditions for up to 5 years. Researchers will track symptoms, muscle strength, and MRI scans to see how the disease progresses and how surgery affects outcomes. The goal is to le…