Montreal Heart Institute

This study tests whether giving two inhaled drugs (milrinone and epoprostenol) before heart-lung bypass can prevent difficult separation from the machine. About 141 adults having heart surgery will be randomly assigned to receive the drug combo or a placebo. The goal is to see if…

This large phase 3 trial is testing whether colchicine (a gout medication) and low-dose aspirin, taken together or alone, can prevent heart attacks, strokes, and cardiac death in 10,000 high-risk people with type 2 diabetes who have not yet had a heart-related event. Participants…

This study tests whether taking only the blood thinner ticagrelor (instead of the usual combination of ticagrelor plus aspirin) can reduce bleeding after a heart attack. It involves 2,570 adults who had a heart attack but did not receive stents or bypass surgery. Participants wil…

This study looks at whether changing the dose or form of aspirin can improve blood clotting control in people with type 2 diabetes who don't respond well to standard enteric-coated aspirin. About 30 participants will try three different aspirin regimens over several weeks. The ma…

This study tests a personalized hydration strategy to prevent contrast-induced acute kidney injury (CI-AKI) in adults undergoing coronary angiogram or PCI. Participants receive intravenous saline at rates adjusted based on their heart pressure, contrast dose, and kidney function.…

This study tests whether soaking your feet in hot water for 12 weeks can improve blood sugar control and blood vessel function in adults with type 2 diabetes. Researchers will compare hot water foot baths to neutral temperature foot baths in 44 people aged 45-75. The goal is to s…

This study tests whether combining cognitive training (brain games) with physical exercise can improve thinking, memory, and brain blood flow in people with chronic heart failure. Researchers will enroll 216 men and women aged 50 and older with stable heart failure. Participants …

This study will check whether cholesterol test results are reliable throughout a hospital stay for a heart attack. Researchers will measure cholesterol levels in 100 patients at the start of their stay, two days later, and again 4-6 weeks after discharge. The goal is to see if a …

This study uses artificial intelligence to analyze data from 21,000 patients who had heart valve procedures. The goal is to make AI tools that can predict surgery outcomes, like which device to use and risks of complications, with over 90% accuracy. This is a non-interventional s…