Merck Sharp & Dohme Llc

This study tested an experimental drug called MK-6194 in adults with non-segmental vitiligo, a condition that causes white patches on the skin. The goal was to see if the drug could reduce the amount of vitiligo on the face compared to a placebo, and to check its safety. The stud…

This study tested a personalized mRNA vaccine (mRNA-4157) combined with the immunotherapy drug pembrolizumab for people with advanced skin cancer that could be removed by surgery. The goal was to see if the combination worked better than standard treatment or pembrolizumab alone.…

This study tested whether adding the immunotherapy drug pembrolizumab (Keytruda) to precise radiation therapy (SBRT) could help people with early-stage non-small cell lung cancer who couldn't have surgery. The trial was stopped early, so results are limited. It involved 448 adult…

This study tested a new monthly pill (islatravir) to see if it could prevent HIV infection better than the daily standard medication. It included 730 cisgender women at high risk for HIV. The trial was terminated early, so results are limited.

This early-stage study tested an experimental drug called MK-6552 in 9 people with narcolepsy type 1, a condition that causes sudden sleep attacks. The goal was to see if the drug could help them stay awake longer during the day and to check for side effects. The trial was stoppe…

This study tested an experimental drug called MK-1942 in about 99 adults with treatment-resistant depression (depression that doesn't get better with usual antidepressants). Participants took MK-1942 (daily or intermittently) or a placebo pill alongside their current antidepressa…