Medtronic Cardiovascular

This study compares two types of TAVR devices (self-expanding vs. balloon-expandable) in over 1,100 people with severe aortic stenosis and a small aortic annulus. The goal is to see which device leads to fewer deaths, strokes, or hospitalizations, and which performs better over t…

This study compared two treatments for severe aortic stenosis, a condition where the heart's main valve tightens and restricts blood flow. About 1,700 patients at intermediate surgical risk were randomly assigned to either a less invasive catheter-based valve replacement (TAVI) o…

This study tests whether a less invasive heart valve replacement (TAVR) is safe and effective for people with moderate aortic stenosis, a condition where the heart's aortic valve is partially blocked. About 650 participants will receive the TAVR device and be monitored for compli…

This study looks at a less invasive procedure called TAVR to replace the heart valve in 150 people who have a bicuspid aortic valve (a common birth defect) and severe narrowing. The goal is to see if TAVR is safe and works well for these patients, who are at low risk for open-hea…

This study looks at how well the Harmony Transcatheter Pulmonary Valve (TPV) works when used by doctors in everyday practice. It involves 174 people with congenital heart disease who need a new pulmonary valve. The main goal is to see if the valve works properly without needing a…

This study tests a new heart valve device (Medtronic CoreValve Evolut PRO) in 52 Chinese patients with severe aortic stenosis who are too high-risk for open-heart surgery. The goal is to see if the device is safe and effective at replacing the damaged valve without major surgery.…

This study tests whether a less invasive procedure called TAVR (replacing the aortic valve through a tube in an artery) is as safe and effective as open-heart surgery for people with severe aortic stenosis who are otherwise healthy enough for surgery. About 2,200 participants wil…

This study tests a new device called the Intrepid Transcatheter Mitral Valve Replacement System for people with severe mitral regurgitation (a leaky heart valve) who are too high-risk for open-heart surgery. The goal is to see if the device is safe and works well. About 128 parti…

This study tests a special chimney graft technique for people with a type of aortic aneurysm that is hard to treat because it is close to the kidneys. The goal is to see if this method is safe and works well in everyday medical practice. About 150 adults will take part, and resea…