New heart valve procedure offers hope for High-Risk patients

NCT ID NCT02322840

Ongoing Disease control Sponsor: Medtronic Cardiovascular Source: ClinicalTrials.gov ↗

First seen Nov 25, 2025 · Last updated Apr 30, 2026 · Updated 28 times

Summary

This study tests a new device called the Intrepid Transcatheter Mitral Valve Replacement System for people with severe mitral regurgitation (a leaky heart valve) who are too high-risk for open-heart surgery. The procedure uses a thin tube inserted through a vein in the leg to place the new valve, avoiding major surgery. The goal is to see if the device is safe and works well in 128 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abbott Northwestern Hospital - EFS

Minneapolis, Minnesota, 55407, United States
Abbott Northwestern Hospital - PILOT

Minneapolis, Minnesota, 55407, United States
Abrazo Arizona Heart Hospital - EFS

Phoenix, Arizona, 85016, United States
Aurora Saint Luke's Medical Center - EFS

Milwaukee, Wisconsin, 53215, United States
Aurora Saint Lukes Medical Center - PILOT

Milwaukee, Wisconsin, 53215, United States
Barnes Jewish Hospital - PILOT

St Louis, Missouri, 63110, United States
Baylor Jack and Jane Hamilton Heart and Vascular Hospital - PILOT

Dallas, Texas, 75246, United States
Cedars-Sinai Medical Center - PILOT

Los Angeles, California, 90048, United States
Centre Hospitalier Régional Universitaire de Lille - PILOT

Lille, France
Clinique Pasteur - PILOT

Toulouse, France
Corewell Health - EFS

Grand Rapids, Michigan, 49503, United States
Guys & St Thomas NHS Foundation Trust - St Thomas Hospital - PILOT

London, United Kingdom
Helsinki University Hospital - PILOT

Helsinki, FL-00029 HUS, Finland
Houston Methodist Hospital - PILOT

Houston, Texas, 77030, United States
Hygeia Hospital - PILOT

Athens, Greece
Monash Health - PILOT

Clayton, Victoria, 3168, Australia
NYU Langone Medical Center - PILOT

New York, New York, 10016, United States
New York-Presbyterian Hospital Columbia University Medical Center - EFS

New York, New York, 10032, United States
New York-Presbyterian Hospital Columbia University Medical Center - PILOT

New York, New York, 10032, United States
Northwestern Memorial Hospital - PILOT

Chicago, Illinois, 60208, United States
Oregon Health & Science University Hospital - EFS

Portland, Oregon, 97239, United States
Piedmont Atlanta Hospital - PILOT

Atlanta, Georgia, 30309, United States
Rigshospitalet - PILOT

Copenhagen, Denmark
Royal Prince Alfred Hospital - PILOT

Sydney, Australia
Royal Sussex County Hospital - PILOT

Brighton, United Kingdom
The Alfred Hospital - PILOT

Melbourne, Australia
The Leeds Teaching Hospitals NHS Trust - Leeds General Infirmary - PILOT

Leeds, LS1 3EX, United Kingdom
The Mount Sinai Hospital (New York NY) - EFS

New York, New York, 10029, United States
The Mount Sinai Hospital (New York NY) - PILOT

New York, New York, 10029, United States
UPMC Pinnacle Harrisburg Campus - EFS

Wormleysburg, Pennsylvania, 17043, United States
University of Michigan Health System - University Hospital - PILOT

Ann Arbor, Michigan, 48109, United States
University of Virginia Medical Center - EFS

Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.

MITRAL VALVE INSUFFICIENCY