New heart valve clip could spare patients from Open-Heart surgery
NCT ID NCT05927441
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests the DragonFly device, a clip that repairs leaky mitral valves without open-heart surgery. It enrolls 168 people with moderate-to-severe mitral regurgitation who are too high-risk for surgery. The goal is to see if the device safely controls the leak and reduces heart failure symptoms over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DragonFly Transcatheter Mitral Valve Repair System (a device that clips the mitral valve to stop leakage)
What this could lead to
If successful, this device could offer a less invasive way to control mitral regurgitation and reduce heart failure symptoms without open-heart surgery.
What could go wrong
This is an early-stage study with no control group, so results may not prove superiority over existing treatments. Risks include procedural complications, device failure, or no improvement in heart function.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Universitatsklinikum Bonn Medizinische Klinik und Poliklinik
RECRUITINGBonn, Germany