Less invasive heart valve procedure tested as alternative to major surgery

NCT ID NCT02701283

Ongoing Disease control Sponsor: Medtronic Cardiovascular Source: ClinicalTrials.gov ↗

Summary

This study tested a less invasive procedure called TAVR against traditional open-heart surgery for replacing a severely narrowed aortic valve. It involved over 2,200 patients who were considered at low risk for complications from surgery. The main goal was to see if the TAVR procedure was as safe and effective as surgery over two years, specifically looking at rates of death or serious stroke.

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Contacts and locations

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Locations

Abbott Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Abrazo Arizona Heart Hospital

Phoenix, Arizona, 85016, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Baylor Jack and Jane Hamilton Heart and Vascular Hospital

Dallas, Texas, 75204, United States
Baylor Saint Luke's Medical Center

Houston, Texas, 77030, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Catharina Ziekenhuis

Eindhoven, 5623, Netherlands
Centre Hospitalier Régional Universitaire de Lille

Lille, 59000, France
Clinique Pasteur

Toulouse, 31300, France
Delray Medical Center

Delray Beach, Florida, 33484, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
El Camino Hospital

Mountain View, California, 64040, United States
Erasmus Medisch Centrum

Rotterdam, 3015, Netherlands
Fiona Stanley Hospital (FSH)

Murdoch, Western Australia, 6150, Australia
Geinsinger Medical Center

Danville, Pennsylvania, 17043, United States
Glen Royal Victoria (McGill)

Montreal, Quebec, H4A 3J1, Canada
Good Samaritan Hospital

Cincinnati, Ohio, 45220, United States
HealthPark Medical Center

Fort Myers, Florida, 33908, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
IUCPQ

Québec, Quebec, G1V 4G5, Canada
Integris Baptist Medical Center

Oklahoma City, Oklahoma, 73112, United States
Jewish Hospital

Louisville, Kentucky, 40202, United States
Kokura Memorial Hospital

Kitakyushu, Fokuoka, Japan
L'Hôpital Privé Jacques Cartier Massy

Massy, 91300, France
Lehigh Valley Hospital

Allentown, Pennsylvania, 18103, United States
London Health Sciences Centre

London, Ontario, N6A 5A5, Canada
Los Robles Hospital & Medical Center

Thousand Oaks, California, 91360, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
MedStar Union Memorial Hospital

Baltimore, Maryland, 21218, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Mercy General Hospital

Sacramento, California, 95816, United States
Mercy Hospital

Springfield, Missouri, 65806, United States
Mercy Medical Center

Des Moines, Iowa, 50314, United States
Methodist Hospital San Antonio

San Antonio, Texas, 78229, United States
Monash Health

Clayton, Victoria, 3168, Australia
Montreal Heart

Montreal, H1T 1C8, Canada
Morton Plant Hospital

Clearwater, Florida, 33756, United States
National Cerebral and Cardiovasclular Center

Suita, Osaka, Japan
Northwell Health

Manhasset, New York, 11030, United States
OhioHealth Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Oregon Health Science University

Portland, Oregon, 97239, United States
Paramount Heart

Villanova, Pennsylvania, 19085, United States
Piedmont Atlanta Hospital

Atlanta, Georgia, 30309, United States
Pinnacle Health

Harrisburg, Pennsylvania, 17043, United States
Royal North Shore Hospital

St Leonards, New South Wales, 2065, Australia
Saint Francis Hospital

East Hills, New York, 11548, United States
Saint John Hospital and Medical Center

Detroit, Michigan, 48236, United States
Saint Joseph's Hospital Health Center

Liverpool, New York, 13088, United States
Saint Mary's Hospital

Richmond, Virginia, 23226, United States
Saint Vincent Heart Center of Indiana

Indianapolis, Indiana, 46290, United States
Saint Vincent's Hospital Sydney

Darlinghurst, New South Wales, 2010, Australia
Sakakibara Heart Institute

Fuchū, Tokyo, Japan
Sanford Medical Center

Fargo, North Dakota, 58102, United States
Sapporo Higashi Tokushukai Hospital

Sapporo, Hokkaido, Japan
Scripps Memorial Hospital La Jolla

La Jolla, California, 92037, United States
Sendai Kousei Hospital

Sendai, Miyagi, Japan
Shonan Kamakura General Hospital

Kamakura, Kanagawa, Japan
Spectrum Health Hospitals

Grand Rapids, Michigan, 49503, United States
St. Antonius Hospital Nieuwegein

Nieuwegein, 3435, Netherlands
Strong Memorial Hospital

Rochester, New York, 14642, United States
Sunnybrook Health Sciences Centre

Toronto, Canada
Swedish Medical Center

Seattle, Washington, 98122, United States
Tallahassee Research Institute, Inc.

Tallahassee, Florida, 32308, United States
Teikyo University Hospital

Tokyo, Itabashi-Ku, Japan
Terrebonne General Medical Center

Houma, Louisiana, 70360, United States
The Alfred Hospital

Melbourne, Victoria, 3004, Australia
The Johns Hopkins Hospital

Baltimore, Maryland, 21287, United States
The Mount Sinai Hospital

New York, New York, 10029, United States
The Ohio State University

Columbus, Ohio, 43210, United States
The University of Kansas Hospital

Kansas City, Kansas, 66160, United States
The University of Osaka Hospital

Suita, Osaka, Japan
The University of Vermont Medical Center

Burlington, Vermont, 05401, United States
Toronto General Health Hospital

Toronto, Ontario, MSG2C4, Canada
University Hospital Salt Lake City Utah

Salt Lake City, Utah, 84132, United States
University Hospitals Case Medical Center

Cleveland, Ohio, 44106, United States
University of Colorado Hospital

Aurora, Colorado, 80045, United States
University of Maryland Medical Center

Baltimore, Maryland, 21201, United States
University of Miami Hospital

Miami, Florida, 33136, United States
University of Michigan Health System

Ann Arbor, Michigan, 48109, United States
University of Pittsburgh Medical Center UPMC Presbyterian

Pittsburgh, Pennsylvania, 15232, United States
University of Southern California University Hospital

Los Angeles, California, 90033, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Waikato Hospital

Hamilton, New Zealand
Wake Forest Baptist Medical Center

Winston-Salem, North Carolina, 27157, United States
Yale New Haven Hospital

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

AORTIC VALVE STENOSIS