Medsir

This phase 2 trial tested a drug called patritumab deruxtecan (HER3-DXd) in 63 patients with breast cancer, lung cancer, or other solid tumors that had spread to the brain or the lining of the brain and spinal cord. The drug is designed to seek out and destroy cancer cells carryi…

This study tested a new drug called giredestrant against the standard drug tamoxifen in 92 premenopausal women with a common type of early breast cancer. Participants took the medication for 15 days before their planned surgery. The goal was to see how well each drug slowed tumor…

This study tested a combination of two drugs, pembrolizumab and lenvatinib, in 43 people with advanced thymic carcinoma or a related thymoma that had worsened after standard chemotherapy. The goal was to see if the combination could stop or slow cancer growth. Participants receiv…

This study tested two treatment plans for people with advanced HR-positive, HER2-negative breast cancer that is aggressive. One group received a drug called abemaciclib plus hormone therapy. The other group started with a short course of chemotherapy, then switched to abemaciclib…

This phase 2 trial tested whether adding loperamide (Imodium) and a white blood cell booster (G-CSF) could reduce severe diarrhea and low white blood cell counts caused by the drug Trodelvy in people with advanced breast cancer. Fifty patients with metastatic triple-negative or l…