Medsir

This study tested two hormone therapies, giredestrant and tamoxifen, in 92 premenopausal women with early-stage breast cancer. Participants took the drug for 15 days before surgery to see how well it slowed tumor growth. The goal was to compare the drugs' effects on cancer cell a…

This study tested a combination of two drugs, pembrolizumab and lenvatinib, in 43 people with advanced thymic carcinoma or a related thymoma that had worsened after standard chemotherapy. The goal was to see if the combination could slow or stop cancer growth. Participants receiv…

This study tested a drug called HER3-DXd in 63 adults with breast or lung cancer that had spread to the brain or the lining around the spinal cord. Participants received the drug every three weeks. The goal was to see if it could shrink brain tumors and help people live longer. T…

This study tested two treatment approaches for people with advanced HR-positive, HER2-negative breast cancer that has spread. One group received a drug called abemaciclib plus hormone therapy, while the other got short-term chemotherapy followed by the same combo. The goal was to…

This study tested whether adding two supportive drugs (loperamide for diarrhea and G-CSF for low white blood cells) could make a common chemotherapy drug, sacituzumab govitecan, easier to tolerate. It involved 50 adults with advanced triple-negative or luminal breast cancer that …