Lundquist Institute For Biomedical Innovation At Harbor-ucla Medical Center

This study was designed to test whether a combination of an educational booklet, team-based care from a rheumatologist, physical therapist, and psychologist, plus nurse-led phone calls and home symptom tracking, could help more Hispanic adults with rheumatoid arthritis achieve re…

This study tests a new antibiotic called omadacycline, taken once a day by mouth, against standard antibiotics for bone and joint infections. About 180 adults with these infections will be randomly assigned to receive either omadacycline or the usual care. The goal is to see if o…

This study was designed to test whether carefully controlling the amount of breast milk or formula given to babies of overweight mothers could prevent them from becoming obese later in childhood. Researchers planned to enroll mother-infant pairs where the mother had a high BMI. H…

This study tests whether adalimumab, a drug used for arthritis, can reduce pain and improve joint movement in people with MPS I, II, or VI. It includes children and adults aged 5 and older who have significant pain and limited joint motion. Participants receive either adalimumab …

This study looks at how diet and exercise affect the epigenome—chemical marks on DNA—in sperm of overweight Hispanic men. Researchers will compare sperm from 20 healthy active men and 80 obese inactive men before and after a 12-week program of diet, exercise, or both. They will a…

This study looks at how not getting enough sleep changes stress and sex hormones in healthy adults aged 60 to 80. Researchers will measure cortisol and testosterone levels before and after four nights of limited sleep. The goal is to better understand the body's hormone response …

This study was designed to understand how obstructive sleep apnea (OSA) speeds up the natural drop in testosterone as men age. Researchers planned to use CPAP machines—one real, one placebo—to test hormone changes in men aged 30 to 70 with moderate to severe OSA. However, the stu…