Lifestyle changes may rewire sperm DNA, study suggests

NCT ID NCT04175678

First seen Mar 16, 2026 · Last updated May 16, 2026 · Updated 10 times

Summary

This study looks at how diet and exercise affect the epigenome (chemical tags on DNA) in sperm of overweight, inactive Hispanic men. Researchers compare sperm from healthy active men and obese inactive men, then track changes after 12 weeks of diet, exercise, or both. The goal is to see if lifestyle can reverse unhealthy sperm epigenetics, which may impact future fertility.

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Contacts and locations

Locations

  • The Lundquist Institute

    Torrance, California, 90502, United States

Conditions

Explore the condition pages connected to this study.