Leiden University Medical Center

This study tested a new way of clamping the umbilical cord in very preterm babies (born before 30 weeks). Instead of clamping after a fixed time, doctors waited until the baby was stable—heart rate above 100 and oxygen levels normal. The goal was to see if this approach helps mor…

This study tested whether a simple checklist and blood test (the YEARS algorithm) can safely rule out pulmonary embolism (a blood clot in the lungs) in people with active cancer, compared to the standard approach of doing a CT scan on everyone. About 700 cancer patients with susp…

This study tested whether a clinical decision rule, combining a 5-question heart score with a rapid blood test, could safely reduce unnecessary hospital referrals for chest pain. Nearly 950 adults with new chest pain were seen by their general practitioner. The goal was to see if…

This study tested a nurse-led education program for dry mouth in 70 patients with life-limiting conditions or frailty. Nurses used guidelines to discuss causes and treatments with patients, creating a personalized plan. The goal was to see if this approach reduces dry mouth sever…

This study looked at whether teaching primary care doctors better ways to treat insomnia can help their patients sleep better. About 485 patients with insomnia symptoms completed surveys. Researchers compared patients whose doctors received special training with those getting usu…

This study looked at whether giving a lower dose of the steroid dexamethasone before the chemotherapy drug docetaxel can prevent allergic reactions with fewer side effects. The standard high dose can cause problems like high blood sugar, mood changes, and weakened immunity. Resea…

This study tested a virtual coach delivered through a smartphone app to help adults quit smoking and increase physical activity. One hundred participants used the coach for about 16 weeks, with personalized chat conversations and exercises. The goal was to see if the program is f…

This study looked at data from over 1000 preterm babies with low platelet counts to build a model that predicts their risk of major bleeding or death. The goal is to help doctors decide when a platelet transfusion is truly needed, since current guidelines based only on platelet c…