New model may help decide which preterm babies need platelet transfusions
NCT ID NCT06043050
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This study looked at data from over 1000 preterm babies with low platelet counts to build a model that predicts their risk of major bleeding or death. The goal is to help doctors decide when a platelet transfusion is truly needed, since current guidelines based only on platelet count may not be enough. The model considers each baby's changing condition over time to give personalized risk estimates.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Platelet transfusion
What this could lead to
If successful, this model could help doctors decide which preterm babies truly need platelet transfusions, reducing unnecessary treatments and complications.
What could go wrong
This is an observational study, not a trial, so it can't prove cause and effect. The model needs further testing before it can be used in practice.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Amsterdam University Medical Center, Emma Children's hospital, location AMC
Amsterdam, North Holland, 1105 AZ, Netherlands
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Amsterdam University Medical Center, Emma Children's hospital, location VUmc
Amsterdam, North Holland, 1081 HV, Netherlands
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Charité - Universitätsmedizin Berlin
Berlin, Metropolregion Berlin-Brandenburg, 10117, Germany
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Erasmus University Medical Center, Sophia pediatric hospital
Rotterdam, South Holland, 3015 CN, Netherlands
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Isala clinics
Zwolle, Overijssel, 8025 AB, Netherlands
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Karolinska University Hospital
Stockholm, Södermanland and Uppland, 171 76, Sweden
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Leiden University Medical Center, Willem Alexander Children's hospital
Leiden, South Holland, 2333 ZA, Netherlands
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Maastricht University Medical Center, MosaKids
Maastricht, Limburg, 6229 HX, Netherlands
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Máxima Medical Center
Veldhoven, North Brabant, 5504 DB, Netherlands
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Radboud University Medical Center, Amalia Children's hospital
Nijmegen, Gelderland, 6525 GA, Netherlands
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University Medical Center Groningen, Beatrix Children's hospital
Groningen, Provincie Groningen, 9713 GZ, Netherlands
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University Medical Center Utrecht, Wilhelmina Children's hospital
Utrecht, Utrecht, 3584 EA, Netherlands