Draining fluid early after brain bleed may boost recovery

NCT ID NCT07625449

Not yet recruiting Disease control Sponsor: Second Affiliated Hospital of Nanchang University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether adding early lumbar drainage to standard care (a drain in the head plus clot-dissolving medication) improves long-term outcomes for people with bleeding into the brain's fluid-filled spaces. The study includes adults aged 18 to 85 who have had a first-time brain bleed with ventricular involvement and require a ventricular drain. Participants are randomly assigned to receive either standard care alone or standard care plus early lumbar drainage, and their functional recovery is measured at 90 and 180 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lumbar drainage
What this could lead to: If effective, early lumbar drainage could become a standard addition to treatment, reducing disability and improving recovery after ventricular hemorrhage.
What could go wrong: This is a relatively early-stage trial with 392 participants, and the procedure carries risks such as infection or over-drainage. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intracerebral hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL HEMORRHAGE INTRAVENTRICULAR HEMORRHAGE

Contacts and locations

Locations

Changde First People's Hospital

Changde, China
Fuzhou First People's Hospital

Fuzhou, Jiangxi, China
Ganzhou People's Hospital

Ganzhou, China
Ji'an Central People's Hospital

Ji’an, China
Jingdezhen Second People's Hospital

Jingdezhen, China
Jiujiang First People's Hospital

Jiujiang, China
Lingcheng District People's Hospital

Dezhou, China
Linyi People's Hospital

Linyi, China
Nanchang Central Hospital

Nanchang, China
Panzhihua Central Hospital

Panzhihua, China
Qilu Hospital of Shandong University Dezhou Hospital

Dezhou, China
Ruijin People's Hospital

Ganzhou, China
Second Affiliated Hospital of Nanchang University

Nanchang, China
Taihe Hospital

Shiyan, China
The 904th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army

Suzhou, China
The Affiliated Hospital of Guizhou Medical University

Guiyang, China
The Affiliated Hospital of Southwest Medical University

Luzhou, China
The First Affiliated Hospital of Anhui Medical University

Hefei, China
The First Affiliated Hospital of Gannan Medical University

Ganzhou, China
The First Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, China
The First People's Hospital of Xiushui County

Jiujiang, China
The Second Affiliated Hospital of Wenzhou Medical University

Wenzhou, China
The Second Hospital of Lanzhou University

Lanzhou, China
Yichang Central People's Hospital

Yichang, China
Yingtan People's Hospital

Yingtan, China
Zhangjiagang First People's Hospital

Zhangjiagang, China
Zhangshu People's Hospital

Yichun, China
Zhoukou Central Hospital

Zhoukou, China
Zunyi First People's Hospital

Zunyi, China

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