Kyowa Kirin Co., Ltd.

This study tests whether KHK4951 eye drops can improve vision in people with diabetic macular edema (DME), a condition where fluid builds up in the eye due to diabetes. About 150 adults with DME will use the eye drops daily for several months. The goal is to see if the drops can …

This early-stage study tests a new drug called KK4277 in healthy volunteers and people with lupus (SLE or CLE). The main goal is to check if the drug is safe and tolerable. Researchers will also measure how the drug moves through the body. The study does not aim to cure lupus, bu…

This study tests whether KHK4951 eye drops can safely improve vision in people with wet age-related macular degeneration (nAMD), a leading cause of vision loss. About 180 participants will use the eye drops or a placebo for several months. The goal is to see if the drops can redu…

This study tests an experimental drug called ME-401 in 61 Japanese adults with a type of slow-growing blood cancer (indolent B-cell non-Hodgkin's lymphoma) that has come back or not responded to at least two prior treatments. The main goal is to see how many patients' tumors shri…

This study follows 226 people with X-linked hypophosphatemia (XLH) for up to 10 years. Researchers will collect information on height, walking ability, fractures, and daily life challenges to better understand how the disease changes over time and affects patients physically and …

This study follows people with aplastic anemia who previously received romiplostim in earlier clinical trials. The goal is to see how well their blood cell counts recover over up to 5 years and to monitor any long-term side effects. No new treatment is given; participants are sim…