Istituto Clinico Humanitas

This phase 2 trial tests whether a precise, high-dose radiation technique called SBRT can lower the chance of cancer coming back in the pancreas area after surgery. The study involves 50 adults with pancreatic cancer who had surgery and are at high risk of recurrence. They will r…

This study looks at whether men with certain gene mutations (DRG) could benefit from a more tailored screening for prostate cancer. Researchers will test a combination of a blood test (PHI) and a special MRI scan in 320 men with or at risk for prostate cancer. The goal is to see …

This study observes 60 adults undergoing open pancreatic surgery to see if low blood pressure during the operation is linked to higher lactate levels afterward. Lactate is a marker of how well tissues are getting oxygen. The goal is to find patterns that could help doctors adjust…

This study looks at how things in the environment and at work might affect people with interstitial lung diseases (a group of lung conditions). Researchers will ask 1,000 adults with a new diagnosis about their exposures to things like pollution, chemicals, and dust. The goal is …

This study follows 250 Italian adults with genetic forms of pulmonary fibrosis to see how their lung function changes over time. Researchers will track breathing tests and compare patients who receive immune-modulating drugs with those who do not. The goal is to understand how in…

This study tests whether artificial intelligence (AI) can analyze medical scans (CT, MRI, PET) to predict how well head and neck cancer patients will respond to radiation therapy and whether they will have side effects. The goal is to personalize treatment for better outcomes. Ab…

This study looks at 266 adults with advanced rectal cancer who had radiation therapy followed by surgery. It compares standard chemoradiotherapy or short-course radiotherapy with a newer approach called total neoadjuvant treatment (TNT). The goal is to see which method leads to f…

This study is creating and testing an Italian version of the ICU Mobility Scale, a tool that measures how well patients in intensive care can move. Researchers will enroll 100 adults in Italian ICUs to see if the scale is accurate and reliable when used by different healthcare wo…