Ionis Pharmaceuticals, Inc.

This early-stage study tested a new drug called BIIB094 in 62 adults with Parkinson's disease. The drug was given as an injection into the spinal fluid to see if it is safe and how the body processes it. The main goal was to check for side effects, not to treat the disease. This …

This study looked at the long-term safety and effectiveness of a drug called donidalorsen for people with hereditary angioedema (HAE), a condition that causes sudden, severe swelling. Twenty adults who had already completed an earlier study received the drug as a shot under the s…

This study tested a new medicine called olezarsen in 617 adults with severely high triglycerides, a type of blood fat that raises the risk of heart problems and pancreatitis. Participants received either the drug or a placebo as a shot under the skin. The main goal was to see if …

This study tested a new medicine called olezarsen in about 1,500 adults with very high triglycerides (a type of blood fat) who also had heart disease or were at high risk for it. The goal was to see if olezarsen could lower triglyceride levels more than a placebo over 25 weeks. P…

This study tested a drug called olezarsen in 446 people with very high triglycerides (a type of blood fat). Participants received either the drug or a placebo as a shot under the skin. The main goal was to see if olezarsen could lower triglyceride levels more than placebo. Result…

This study tested an experimental drug called olezarsen in 154 adults with very high triglycerides (a type of blood fat) and either heart disease or a high risk for it. The goal was to see if the drug could safely lower triglyceride levels more than a placebo over 6 and 12 months…