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Ionis Pharmaceuticals, Inc.

Clinical trials sponsored by Ionis Pharmaceuticals, Inc., explained in plain language.

Trials to join now! 10 Not yet finished but already full! 11 Completed 6 Terminated 2
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  • Down syndrome Alzheimer's drug study halted after just one volunteer

    Disease control Terminated

    This study aimed to test the safety of a new drug called ION269 in adults with Down syndrome who also show signs of Alzheimer's disease in their brains. Only one person took part before the study was stopped early. The main goal was to see if the drug caused any side effects or h…

    Phase: PHASE1 • Sponsor: Ionis Pharmaceuticals, Inc. • Aim: Disease control

    Last updated May 14, 2026 12:05 UTC

  • New study aims to unlock secrets of rare genetic disorder

    Knowledge-focused Terminated

    This study looked at people with MECP2 duplication syndrome, a rare genetic condition that affects development and can cause seizures. Researchers measured changes in biomarkers from blood and spinal fluid, and tracked symptoms using surveys and clinical tests. The goal was to be…

    Sponsor: Ionis Pharmaceuticals, Inc. • Aim: Knowledge-focused

    Last updated May 15, 2026 11:57 UTC

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