New Parkinson's drug BIIB094 passes first safety test in small trial

NCT ID NCT03976349

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-stage trial tested the safety of a new drug called BIIB094 in 62 adults with Parkinson's disease. The drug was given as a spinal injection to see if it is safe and how the body processes it. The study included people with and without certain genetic variations. Results will help decide if further testing is warranted.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BIIB094

What this could lead to

If successful, this could point toward a new treatment option for Parkinson's disease by targeting a genetic pathway.

What could go wrong

This is a very early Phase 1 trial focused on safety, not effectiveness. It is small (62 people) and may not lead to a working treatment. Side effects from the spinal injection are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alliance for Multispecialty Research

    Knoxville, Tennessee, 37920, United States

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hospital General Universitario Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital General de Catalunya

    Barcelona, Vizcaya, 08195, Spain

  • Inland Northwest Research

    Spokane, Washington, 99202, United States

  • Laboratorios de Investigación Biocruces 3., Hospital de Cruces

    Barakaldo, Bizkaia, 48903, Spain

  • Montreal Neurological Institute and Hospital

    Montreal, Quebec, QC H3A 2B4, Canada

  • Neuro-SysMed Center

    Bergen, 5053, Norway

  • Northwestern University PD and Movement Disorders Center

    Chicago, Illinois, 60611, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Queen Square (Neurology) CRF Site Institute of Neurology & the National Hospital for Neurology and Neurosurgery UCLH

    London, WC1N 3BG, United Kingdom

  • Quest Research Institute

    Farmington Hills, Michigan, 48334, United States

  • Research Site

    Toronto, Ontario, Canada

  • Research Site

    Seville, Spain

  • Sourasky Medical Center

    Tel Aviv, 64239, Israel

  • St. Olav University Hospital

    Trondheim, 7030, Norway

  • The Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19107, United States