Hadassah Medical Organization

This study is for people who have had melanoma removed but are at high risk of it returning. The treatment uses a special vaccine made from modified melanoma cells to train the immune system to find and attack any remaining cancer cells. The goal is to see if this approach is saf…

This study looks at whether a moderate carbohydrate diet (up to 120g per day) can help pregnant women with diabetes who need insulin achieve better blood sugar control compared to the standard high-carb diet. The trial will include 120 pregnant women and track their glucose level…

This study tests a personalized cancer vaccine made from patients' own tumor cells or donor cells. The cells are modified in the lab to boost immune response, then killed and injected eight times over 16 weeks. The goal is to help people with metastatic melanoma, breast, ovarian,…

This early-phase study tests a new cell therapy called HBI0101 CART in 60 adults with multiple myeloma that has returned or not responded to standard treatments. The therapy uses a patient's own immune cells, modified to attack cancer cells. The main goals are to find the safest …

This early-phase trial tests a personalized cell therapy for people with several types of advanced cancer that have spread and express a specific marker called NY-ESO-1. Participants receive a single infusion of their own immune cells that have been genetically modified to recogn…

This study looks at whether a single dose of zoledronic acid can prevent bone loss that often happens when people start HIV medications. About 110 adults newly diagnosed with HIV will be split into two groups: one gets the drug, the other just gets regular check-ups. Researchers …

This study tests a 6-week remote group program called CRAFT-G for breast cancer survivors who have memory or thinking problems after treatment. Participants attend six online sessions, do computer brain training three times a week, and receive educational materials. The goal is t…

This study tests whether a cannabis oil containing THC and CBD can reduce severe back or kidney pain and the need for strong painkillers. Two hundred adults with acute radicular pain will receive either cannabis oil or a placebo, and their pain and opioid use will be tracked for …

This study tests if watching relaxing virtual reality (VR) scenes before an egg retrieval procedure can lower pain. One hundred women having elective egg freezing will either get standard care or standard care plus a VR relaxation session. Pain levels are measured with a simple 0…

This study tests whether a real-time artificial intelligence (AI) dashboard can help doctors make better decisions during labor for first-time mothers. About 400 women will be randomly assigned to either standard care or care with the AI tool visible in their medical records. The…

This study looks at how genetic differences affect the way healthy adults process the blood thinner warfarin. Researchers will give participants single doses of warfarin and other drugs to measure enzyme activity and link it to their DNA. The goal is to better understand why peop…

This early-stage study is testing whether adding D-serine to psilocybin (the active ingredient in magic mushrooms) can reduce its psychedelic effects while keeping it safe. Ten healthy adults aged 25-60 will receive one of two dose combinations and be closely monitored for side e…