Guangdong Provincial People's Hospital

This early-stage trial is testing whether a single infusion of universal STAR-T cells—a type of engineered immune cell that targets both CD19 and BCMA—can safely and effectively treat two autoimmune kidney diseases: IgA nephropathy and primary membranous nephropathy. The study wi…

This phase 3 trial is testing whether giving four cycles of chemotherapy combined with targeted therapy (trastuzumab and pertuzumab) before surgery works as well as the standard six cycles for people with intermediate-risk HER2-positive breast cancer. The goal is to see if a shor…

This phase 2 trial is testing whether adding two extra drugs—bevacizumab and sintilimab—to the usual combination of irinotecan and cetuximab can shrink tumors in people with advanced colorectal cancer that no longer responds to irinotecan. The study enrolls 160 adults with RAS wi…

This trial investigates whether adding two targeted drugs—tafolecimab and sintilimab—to standard chemoradiation can improve outcomes for people with locally advanced rectal cancer that has not spread. Participants receive short-course radiation followed by chemotherapy plus immun…

This study tests a new treatment plan for adults with locally advanced rectal cancer that hasn't spread. Participants get a week of radiation, then 8 cycles of three drugs (chemotherapy and immunotherapy) before surgery. The goal is to shrink the tumor enough to cure the cancer o…

This study tests a new treatment for advanced stomach cancer that has spread to the lining of the abdomen. It compares standard chemotherapy given as a spray inside the belly (PIPAC) with a virus-based therapy (VRT106) given the same way. The goal is to see which is safer and wor…

This phase 2 trial tests a sequence of targeted therapy (garsorasib), immunotherapy (ivonescimab), and chemotherapy before and after surgery for people with a specific type of lung cancer (KRAS G12C mutation) that can be removed. The goal is to see if this approach increases the …

This study tests a new CPR method called Bio-CPR, which synchronizes chest compressions with ventilation using a machine. Researchers will compare it to standard CPR in 408 adults who have a witnessed cardiac arrest. The goal is to see if this coordinated approach improves breath…

This study will compare three different artificial intelligence (AI) models that analyze chest CT scans to predict whether a lung nodule is cancerous. The trial will enroll 3,000 adults with small lung nodules (≤3 cm) who have a definitive diagnosis from biopsy or surgery. Each A…

This trial tests whether terbinafine, a common antifungal drug, can prevent acute kidney injury in adults undergoing heart surgery with a heart-lung machine. Participants at high risk of kidney damage will receive terbinafine or a placebo before and after surgery. The study track…

This study tests whether hyperbaric oxygen therapy—breathing pure oxygen in a pressurized chamber—can reduce nerve pain and numbness caused by the chemotherapy drug nab-paclitaxel in breast cancer patients. About 160 women who have finished chemo and developed nerve symptoms will…

This study is exploring whether the bacteria in your gut can predict how well a certain type of lung cancer responds to treatment. Researchers are following 100 people with stage II-IIIB non-small cell lung cancer who are receiving chemoimmunotherapy before surgery. The goal is t…

This study will follow 100 lung cancer patients after surgery to see if levels of CEA and ctDNA in the blood can predict whether the cancer comes back. Participants will have regular blood tests and imaging over two years. The goal is to catch recurrence earlier and tailor follow…