Can pressurized oxygen soothe chemo nerve pain?
NCT ID NCT07410169
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether hyperbaric oxygen therapy—breathing pure oxygen in a pressurized chamber—can reduce nerve pain and numbness caused by the chemotherapy drug nab-paclitaxel in breast cancer patients. About 160 women who have finished chemo and developed nerve symptoms will receive either hyperbaric oxygen sessions or standard care. The goal is to see if this treatment improves their quality of life and eases neuropathy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber)
- What this could lead to
- If it works, this could offer a non-drug way to relieve nerve pain and numbness caused by chemotherapy, improving daily life for breast cancer survivors.
- What could go wrong
- This is a mid-stage trial with only 160 participants, so results may not apply to everyone. Hyperbaric oxygen can cause ear pain or sinus discomfort, and it is not yet proven to help this condition.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China
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