Georgetown University

This study tested a low dose of nilotinib, a drug normally used for leukemia, in 37 people with mild-to-moderate Alzheimer's. The goal was to see if the drug is safe and whether it can reach the brain and affect proteins linked to Alzheimer's. Participants took the drug or a plac…

This study tested a new combination of drugs (ABT-888 plus chemotherapy) in 64 people with pancreatic cancer that had spread. The goal was to see if adding ABT-888, which blocks cancer cells from repairing damage, could shrink tumors better than chemo alone. Participants had to h…

This study tested a combination of two drugs, LEE011 and everolimus, in 12 people with advanced pancreatic cancer that had stopped responding to standard chemotherapy. The goal was to find the best dose and see if the combo could slow cancer growth. The approach aims to control t…

This study tested the drug nilotinib, already approved for leukemia, in 43 people with Dementia with Lewy Bodies (DLB). The main goal was to see if the drug is safe and tolerable in this group. Researchers also measured changes in brain proteins and amyloid plaques using spinal f…

This study tested a software platform called OR PathTrac that tracks how bacteria spread during surgery. The goal was to help hospitals improve their cleaning and infection control steps to lower the risk of surgical site infections. Over 800 adults having surgery took part. The …