Fudan University

This study tests a new drug called cadonilimab combined with standard chemotherapy and radiation for people with stage III non-small cell lung cancer that cannot be removed by surgery. The goal is to see if this combination can shrink tumors and control the disease better. About …

This study tests whether adding stereotactic radiotherapy (precise radiation) to standard targeted therapy can better control brain metastases in people with non-small cell lung cancer. About 202 participants whose brain tumors did not fully shrink after 3-6 months of a third-gen…

This study compares 4 months versus 6 months of chemotherapy (capecitabine and oxaliplatin) in 1024 stomach cancer patients who had surgery. The goal is to see if the shorter treatment works just as well to prevent cancer from coming back, while causing fewer side effects. Partic…

This study tests a combination of the targeted drug abemaciclib with standard chemotherapy (FOLFOX or FOLFIRI) in 16 adults with advanced colorectal cancer that has spread to the liver and hasn't responded to at least two prior treatments. The goal is to see if this combo can shr…

This study tests a two-step treatment for people with early-stage MALT lymphoma, a slow-growing cancer of the lymph nodes. First, patients take a targeted drug called orelabrutinib. Then, based on how well the tumor responds, they receive an ultra-low dose of radiation (4Gy) to a…

This study tests whether a special low-calorie diet, called a fasting-mimicking diet, given before and after surgery can improve recovery and reduce cancer return in people with colorectal cancer. The diet is designed to be easier than complete fasting, especially for older or fr…

This study tests a mix of chemotherapy, immunotherapy, and gut-friendly supplements for people with advanced esophageal cancer. The goal is to see if this approach can shrink tumors and keep them from growing back. About 50 participants will receive the treatment and be followed …

This study looks at whether adding a precise type of radiation to a targeted cancer pill can help people with a specific lung cancer that has spread to the brain. Researchers reviewed medical records of 300 adults who received both treatments. The goal is to see if the combinatio…

This study tests whether giving targeted drugs based on the genetic makeup of a person's advanced salivary gland cancer can shrink tumors or stop them from growing. About 88 adults with cancer that has spread or come back are enrolled. Researchers are checking how well these trea…

This study aimed to compare three different immunotherapy drug regimens given before and after surgery for people with early-stage non-small-cell lung cancer. The goal was to see which approach best prevented the cancer from coming back. However, the trial was withdrawn before en…

This study tests a combination of three drugs (bevacizumab, nab-paclitaxel, and platinum) as a second treatment for people with advanced non-squamous non-small cell lung cancer that does not have certain gene mutations. The participants' cancer had already gotten worse after firs…

This study compares two chemotherapy regimens for people with non-triple negative breast cancer after surgery. One group receives epirubicin plus cyclophosphamide followed by docetaxel (EC-T), while the other gets paclitaxel plus carboplatin (PCb). The goal is to see which combin…

This study looks at whether testing stool (feces) for certain DNA changes and bacteria genes can help find stomach cancer early. Researchers will follow 3000 people, including those with and without cancer, to see how well the test works. The goal is to improve early diagnosis an…

This study looks at whether artificial intelligence can accurately determine the depth of early esophageal cancer from endoscopic images. Researchers will review past records and images from 890 patients who had their tumors removed. The goal is to see if AI can help doctors deci…

This study looks at whether drinking cola can help relieve sudden food blockages in the esophagus for people with esophageal cancer. About 50 participants will be randomly assigned to drink cola or receive standard care. The main goal is to see if cola improves the chance of clea…

This study tests whether a nurse-led pre-rehabilitation program—including exercise, nutrition, and mental support—can improve recovery in 92 liver cancer patients before surgery. The program starts at least 7 days before hospital admission and continues with standard care after. …

This observational study looks at 100 people with advanced non-small cell lung cancer and fluid around the lungs. Researchers collect blood and lung fluid samples before and during standard treatment to see if tiny particles called exosomes can predict how well the therapy works.…

This study looks at whether PET-CT scans can accurately predict if non-small cell lung cancer has spread to nearby lymph nodes. Researchers will compare scan results with actual tissue samples from surgery in 280 patients. The goal is to see if scans alone can guide treatment dec…

This study uses computer models to predict how giving dengue vaccines to people in Yunnan, China, might reduce the spread of the disease. Researchers will collect blood samples from 220 residents to understand immune responses and test different vaccination plans. The goal is to …

This study looked at 197 people with advanced breast cancer to compare survival when estrogen receptors (ER) are lost versus triple-negative breast cancer. Researchers used a special PET scan to track ER changes. The goal was to understand how these changes affect disease progres…

This study looks at how anemia (low red blood cells) changes blood flow in tiny vessels under the tongue during stomach cancer surgery. Researchers will compare 27 anemic patients with 27 non-anemic patients to see if fluid therapy affects these small vessels differently. The goa…

This study was designed to see if adding chemotherapy to radiation therapy helps people with thymoma or thymic cancer live longer after incomplete tumor removal. It planned to include adults aged 18-75 who had surgery but still had some cancer left. However, the study was withdra…